Publications 2008 - 2013
The FGCN's reseach focuses on six specialist genetic areas, the following scientific papers are also listed based on these six genetic areas:
A: Improving mixed-stain DNA analyses.
B: The relative age of the sample.
C: The cellular origin of the biological sample.
D: The geographical origin of the cell donor.
E: The externally visible characteristics of the cell donor.
F: Constructing detailed DNA reference databases.
Scientific papers - subproject B:
1. Ackermann K, Ballantyne KN, Kayser M. Estimating trace deposition time with circadian biomarkers:
a prospective and versatile tool for crime scene reconstruction. (2010) International Journal of Legal Medicine. DOI 10.1007/s00414-010-0457-1
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Scientific papers - subproject C:
1. Harteveld J, Lindenbergh A, Sijen T. RNA cell typing and DNA profiling of mixed samples: Can cell types and donors be associated? Science and Justice xxx(2013) xxx-xxx
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2. Lindenbergh A, Maaskant P, Sijen T. Implementation of RNA profiling in forensic casework. Forensic Sci Int Genet. 7 (2013) 159-166.
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3. Lindenbergh A, de Pagter M, Ramdayal G, Visser M, Zubakov D, Kayser M, Sijen T. A multiplex (m)RNA-profiling system for the forensic identification of body fluids and contact traces, Forensic Sci. Int.: Genet. (2012) doi 10.1016/j.fsigen.2012.01.009.
4. Visser M., Zubakov D., Ballantyne KN, Kayser M. mRNA-based skin identification for forensic applications. International Journal of Legal Medicine (10 January 2011). (doi: 10.1007/s00414-010-0545-2)
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5. Zubakov D, Boersma AWM, Choi Y, van Kuijk PF, Wiemer EAC, and Kayser M (2010) MicroRNA markers for forensic body fluid identification obtained from microarray screening and quantitative
RT-PCR confirmation. International Journal of Legal Medicine (2010) 124: 217-226, Epub February 2010, DOI 10.1007/s00414-009-0402-3
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6. Zubakov D, Kokshoorn M, Kloosterman A, and Kayser M (2009) New markers for old stains:
stable mRNA markers for blood and saliva identification detected from stains up to 16 years of age. International Journal of Legal Medicine, 123:71–74
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7. Gauvin J, Zubakov D, van Rhee-Binkhorst J, Kloosterman A, Steegers E and Kayser M. Forensic pregnancy diagnostics with placental mRNA markers. International Journal of Legal Medicine, (2010)
124: 13-17, Epub 16 Jan 2009, doi:10.1007/s00414-008-0315-6
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8. Kayser M (2009) Forensic pregnancy testing: a special case in molecular diagnostics. Expert Review
of Molecular Diagnostics, 9(2):105-107
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9. Zubakov D, Hanekamp E, Kokshoorn M, van IJken W and Kayser M (2008) Stable RNA markers for blood and saliva identification revealed from whole genome expression analysis of time-wise degraded stains. International Journal of Legal Medicine, 122(2):135-142
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Scientific papers - subproject D:
1. Oven M van, Ralf A, Kayser M An efficient multiplex genotyping approach for detecting the major worldwide human Y-chromosome haplogroups. International Journal of Legal Medicine DOI 10.1007/s00414-011-0605-2 (Technical note)
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2. Van Oven, M. (2010) Revision of the mtDNA tree and corresponding haplogroup nomenclature. Proceedings of the National Academy of Sciences U.S.A. 107(11):E38-9; author reply e40-1
3. Lao O, Vallone PM, Coble MD, Diegoli TM, van Oven M, van der Gaag KJ, Pijpe J, de Knijff P, and Kayser M (2010) Evaluating self declared ancestry of U.S. Americans with autosomal, Y-chromosomal and mitochondrial DNA. Human Mutation, 31(12): E1875–E1893
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4. Ballantyne KN, van Oven M, Ralf A, Stoneking M, Mitchell RJ, van Oorschot RAH, Kayser M. MtDNA SNP multiplexes for efficient inference of matrilineal genetic ancestry within Oceania. Forensic Sci. Int. Genet. (2011) doi: 10.1016/j.fsigen.2011.08.010.
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5. Nothnagel M, Lu TT, Kayser M, Krawczak M (2010) Genomic and geographic distribution of
SNP-defined runs of homozygosity in Europeans. Human Molecular Genetics (2010)19: 2927-2935,
Advance Access published on May 12, 2010. doi:10.1093/hmg/ddq198
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6. Shi W, Ayub Q, Vermeulen M, Shao R, Zuniga S, van der Gaag K, de Knijff P, Kayser M, Xue Y,
and Tyler-Smith C (2010) Worldwide Survey of Human Male Demographic History Based on Y-SNP and Y-STR Data from the HGDP–CEPH Populations Mol. Biol. Evol. 27(2):385–393. 2010, doi:10.1093/molbev/msp243
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7. Kersbergen P, van Duijn K, Kloosterman AD, den Dunnen JT, Kayser M, de Knijff P (2009) Developing a set of ancestry-sensitive DNA markers reflecting continental origins of humans. BMC Genetics, 10:69, Advanced Online published October 27, 2009, doi:10.1186/1471-2156-10-69
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8. Tims S, van Wamel W, Endtz HP, van Belkum A, and Kayser M (2009) Microbial DNA fingerprinting
of human fingerprints: Dynamic colonization of fingertip microflora challenges human host inferences
for forensic purposes. International Journal of Legal Medicine, Epub June 2009, DOI 10.1007/s00414-009-0352-9
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9. Van Oven M and Kayser M (2009) Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation. Human Mutation, 30 (2):E386-E394
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10. Corach D, Lao O, Bobillo C, van der Gaag K, Zuniga S, Vermeulen M, van Duijn K, Goedbloed M, Vallone PM, Parson W, de Knijff P, and Kayser M (2009) Inferring continental ancestry of Argentineans from autosomal, Y-chromosomal and mitochondrial DNA. Annals of Human Genetics (2010) 74, 65 - 76, Published Online: Dec 15 2009, DOI:10.111/j.1469.2009.00556.x
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Scientific papers - subproject E:
1. Draus-Barini J, Walsh S, Pospiech E, Kupiec T, Glab H, Branicki W, Kayser M. Bona fide colour: DNA prediction of human eye and hair colour from ancient and contemporary skeletal remains Investigative Genetics 2013, 4:3 doi:10.1186/2041-2223-4-3
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3. Walsh S, et al., The HIrisPlex system for simultaneous prediction of hair and eye colour from DNA, Forensic Sci. Int. Genet. (2012), doi: 10.1016/j.fsigen.2012.07.005
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4. Visser M, Kayser M, Palstra R-J. HERC2 rs12913832 modulates human pigmentation by attenuating chromatin-loop formation between a long-range enhancer and the OCA2 promoter Genome Research 22 (2012) 446-455.
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5. Walsh S, Lindenbergh A, Zuniga SB, Sijen T, de Knijff P, Kayser M, and Ballantyne KN (2011) Developmental validation of the IrisPlex System: Determination of blue and brown iris colour for forensic intelligence. Forensic Science International: Genetics., vol 5 (2011) 464-471
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6. Walsh S, Wollstein A, Liu F, Chakravarthy U, Rahu M, Seland JH, Soubrane G, Tomazzoli L Topouzis F, Vingerling JR, Vioque J, Fletcher AE, Ballantyne KN, Kayser M. DNA-based eye colour prediction across Europe with the IrisPlex system. Forensic Sci. Int. Genet. (2011), doi:10.1016/j.fsigen.2011.07.009
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7. Branicki W., Liu F., van Duijn K., Draus-Barini J., Pos´piech E., Walsh S., Kupiec T., Wojas-Pelc A., Kayser M. Model-based prediction of human hair color using DNA variants. Human Genetics Vol. 1 (January) 2011 (doi:10.1007/s00439-010-0939-8).
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8. Liu F, Wollstein A, Hysi PG, Ankra-Badu GA, Spector TD, Park D, Zhu G, Larsson M, Duffy DL, Montgomery GW, Mackey DA, Walsh S, Lao O, Hofman A, Rivadeneira F, Vingerling JR, Uitterlinden AG, Martin NG, Hammond CJ, Kayser M. Digital Quantification of Human Eye Color Highlights Genetic Association of Three New Loci. (2010) PLoS Genetics Volume 6 Issue 5: e1000934.
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9. Walsh S, Liu F, Ballantyne Kaye N, Oven M van, Lao O, Kayser M. *IrisPlex: A sensitive DNA tool for accurate prediction of blue and brown eye colour in the absence of ancestry information Forensic. Forensic Sci. Int. Genet. (2010), doi:10.1016/j.fsigen.2010.02.004 Vol 5-3 (2011) page 170-180
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10. Zubakov D, Liu F, van Zelm MC, Vermeulen J, Oostra BA, C.M. van Duijn CM, Driessen GJ, van Dongen JJM, Kayser M, and Langerak AW. Estimating human age from T-cell DNA rearrangements Current Biology (2010) Vol 20 No 22 R970-971
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11. Liu F, van Duijn K, Vingerling JR, Hofman A, Uitterlinden AG, Janssens ACJW, and Kayser M (2009)
Eye color and the prediction of complex phenotypes from genotypes. Current Biology vol. 19, No 5 R:192-193
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12. Kayser M and Schneider PM (2009) DNA-based prediction of human externally visible characteristics in forensics: motivations, scientific challenges, and ethical considerations. Forensic Science International: Genetics (2009) 3: 154–161, doi:10.1016j/fsi-gen.2009.01.012
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13. Estrada K, Krawczak M, Schreiber S, van Duijn K, Stolk L, van Meurs JBJ, Liu F, Penninx BWJH, Smit JH, Vogelzangs N, Hottenga JJ, Willemsen G, de Geus EJC, Lorentzon M, von Eller-Eberstein H, Lips P, Schoor N, PopV, de Keijzer J, Hofman A, Aulchenko YS, Oostra BA, Ohlsson C, Boomsma DI, Uitterlinden AG, van Duijn CM, Rivadeneira F, Kayser M (2009) A genome-wide association study of northwestern Europeans involves the CNP signaling pathway in the etiology of human height variation. Human Molecular Genetics, 18:3516-3524
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Scientific papers - subproject F:
1. Westen AA, Gaag KJ van der, Knijff P de, Sijen T. Improved analysis of log STR amplicons from degraded single source and mixed DNA. Int. J. Legal Medicine (January 2013) doi 10.1007/s00414-012-0816-1 (Impact factor 2,9).
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2. Westen AA, Grol LJW, Harteveld J, Matai AS, de Knijff P, Sijen T. Assessment of the stochastic threhold, back- and forward stutter filters and low template techniques for NGM. For. Sci. Int Genetics (2012) doi 10.1016/j.fsigen.2012.05.001.
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3. Westen AA, Haned H, Grol LJW, Harteveld J, van der Gaag KJ, de Knijff P and Sijen T. Combining results of forensic STR kits: HDplex validation including allelic association and linkage with NGM and Identifiler loci. Int. J. Legal Medicine (July 2012) doi 10.1007/s00414-012-0724-4
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4. Benschop C, Haned H, Sijen T. Consensus and pool profiles to assist in the analysis and interpretation of complex low template DNA mixtures Int. J. Legal Medicine (2011) doi:10.1007/s00414-011-0647-5
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5. Verheij S, Harteveld J Sijen T. A protocol for direct and rapid multiplex PCR amplification on forensically relevant samples Forensic Sci. Int. Genet. (2011), doi:10.1016/j.fsigen.2011.03.014
6. Ballantyne KN, Goedbloed M, Fang R, Schaap O, Lao O, Wollstein A, Choi Y, van Duijn K, Vermeulen M, Brauer S, Decorte R, Poetsch M,von Wurmb-Schwark N, de Knijff P,Labuda D, Vézina H, Knoblauch H, Lessig R, Roewer L, Ploski R,Dobosz T,Henke L, Henke J, Furtado MR and Kayser M. Mutability of Y-Chromosomal Microsatellites: Rates, Characteristics, Molecular Bases, and Forensic Implications The American Journal of Human Genetics (2010), doi:10.1016/j.ajhg.2010.08.006.
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7. Ballantyne KN , Keerl V, Wollstein A, Choi Y, Zuniga SB, Ralf A, Vermeulen M, de Knijff P, Kayser M. A new future of forensic Y-chromosome analysis: Rapidly mutating Y-STRs for differentiating male relatives and paternal lineages. Forensic Sci. Int. Genet. (2011), doi:10.1016/j.fsigen.2011.04.017
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8. Benschop CCG, van der Beek CP, Meiland HC., van Gorp AGM, Westen AA, Sijen T. Low template STR typing: Effect of replicate number and consensus method on genotyping reliability and DNA database search results. Forensic Science International Genetics (2010), doi:10.1016/j.fsigen.2010.06.006
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9. Westen AA, Matai AS, Laros JFJ, Meiland HC, Jasper M, de Leeuw WJF, de Knijff P, Sijen T (2009)
Tri-allelic SNP markers enable analysis of mixed and degraded DNA samples. Forensic Science International: Genetics (2009) 3: 233-241, doi:10.1016/j.fsi-gen.2009.02.003
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10. Vermeulen M, Wollstein A , van der Gaag K, Lao O, Xue Y, Wang Q, Roewer L, Knoblauch H,
Tyler-Smith C, de Knijff P, and Kayser M (2008) Improving global and regional resolution of male lineage differentiation by simple single-copy Y-chromosomal short tandem repeat polymorphisms. Forensic Science International: Genetics, (2009) 3: 205-213, doi:10.1016/j.fsigen.2009.01
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11. Westen AA, Sijen T, Degraded DNA sample analysis using DNA repair enzymes,
mini-STRs and (tri-allelic) SNPs. Forensic Science International: Genetics Supplemt Series 2 (2009)
blz: 505-507
12. Dieltjes P, Mieremet R, Zuniga S, Kraaijenbrink Th, Pijpe J, de Knijff P. A sensitive method to extract DNA from biological traces present on ammunition for the purpose of genetic profiling Intrnational Journal of Legal Med DOI 10.1007/s00414-010-0454-4
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13. Weiler NEC, Matai AS, Sijen T. Extended PCR conditions to reduce drop-out frequencies in low template STR typing including unequal mixtures Forensic Sci. Int. Genet. (2011), doi:10.1016/j.fsigen.2011.03.002 Vol 6-1 (2012) page 102-107
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Other publications:
1. Kayser M., de Knijff P. Improving human forensics through advances in genetics, genomics and molecular biology. Nature Reviews / Genetics Volume 12 (2011) 179-192
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2. Zubakov D, Liu F, van Zelm MC, Vermeulen J, Oostra BA, C.M. van Duijn CM, Driessen GJ, van Dongen JJM, Kayser M, and Langerak AW. Estimating human age from T-cell DNA rearrangements Current Biology (2010) Vol 20 No 22 R970-971
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3. Ballantyne KN, Kayser M, Grootegoed JA. Sex and gender issues in competitive sports: investigation of a historical case leads to a new viewpoint British Journal of Sports Medicine. (2011). doi:10.1136/2 of 4 bjsm.2010.082552.
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Books:
1. Benschop C. (2012) On the effects of sampling, analysis and interpretation strategies for complex forensic DNA research with focus on sexual assault cases. ISBN: 978-94-91407-03-1
2. Meulenbroek , A.J (2009) De Essenties van forensisch biologisch onderzoek; Humane biologische sporen en DNA (5e ed.) Uigeverij Paris, Zutphen, The Netherlands.
3. Meulenbroek , A.J (2009) Forensisch DNA-onderzoek in de (strafrecht)praktijk; Te onderscheiden fasen en wetenschappelijke bewijswaarde. Nederlands Forensisch Instituut, Den Haag, The Netherlands.
4. Ballantyne K and Kayser M (2009) Forensic molecular diagnostics. In: Molecular Diagnostics: Techniques & Applications, van Leeuwen WB and Vink C (Eds), IVA GROEP BV, Rotterdam,
The Netherlands, 2009, 211-235
5. Lao O and Kayser M (2009) Human relationships inferred from genetic variation.
In: Human Relationships Inferred from Genetic Variation. In: ENCYCLOPEDIA OF LIFE SCIENCES.
John Wiley & Sons, Ltd: Chichester www.els.net [Doi: 10.1002/9780470015902.a0021758]
6. Lao O and Kayser M (2009) Op het eerste gezicht: Hoe het klimaat onze huidskleur dicteerde,
In: Evolutie zit in je genen: over Darwin en genomics. Geraedts JPM, de Knijff P, Everdingen JJE,
van den Broek J, Smits R (Eds), Stichting Bio-Wetenschappen en Maatschappej, Den Haag,
The Netherlands, 2009, 47-54.
7. de Knijff P (2009) DNA verraadt hoe de mens de wereld koloniseerde, In: Evolutie zit in je genen: over Darwin en genomics. Geraedts JPM, de Knijff P, van Everdingen JJE, van den Broek J, Smits R (Eds), Stichting Bio-Wetenschappen en Maatschappij, Den Haag, The Netherlands, 2009, 64 – 67
8. de Knijff P (2009) Aan gene zijde: over forensische genetica, In: Speuren naar sporen. Forensische geneeskunde in Nederland. Bol P, Das K, van Everdingen JJE, de Wolff F (Eds), Stichting bio-
wetenschappen en Maatschappij, Den Haag, The Netherlands, 2009, 38 – 41
De Essenties van forensisch biologisch onderzoek:
Humane biologische sporen
en DNA (in Dutch)
Forensisch DNA-onderzoek in de (strafrecht)praktijk:
Te onderscheiden fasen en wetenschappelijke
bewijswaarde (in Dutch)
